"Understanding a role for hypoxia in lesion formation and location in the deep and periventricular white matter in small vessel disease and multiple sclerosis"
https://www.ncbi.nlm.nih.gov/pubmed/29026001

(An excellent resource to learn about hypoxia in MS is Dr. Philip James's book "Oxygen and the Brain". http://www.hbot.com/blog/edward-lucarini/oxygen-and-brain-dr-philip-james-explains-relationship-his-new-book)

Clin Sci (Lond). 2017 Oct 12;131(20):2503-2524. doi: 10.1042/CS20170981. Print 2017 Oct 15. Review