Iron and Non-Iron-Related Characteristics of Multiple Sclerosis and Neuromyelitis Optica Lesions at 7T MR
Editor’s Choice
Twenty-one patients with MS and 21 patients with neuromyelitis optica underwent 7T high-resolution 2D-gradient-echo-T2* and 3D-susceptibility-weighted imaging. An in-house-developed algorithm was used to reconstruct quantitative susceptibility mapping from SWI. Of the patients with MS, 19 (90.5%) demonstrated at least 1 quantitative susceptibility mapping–hyperintense lesion, and 11/21 (52.4%) had iron-laden lesions. No quantitative susceptibility mapping–hyperintense or iron-laden lesions were observed in any patients with neuromyelitis optica. The authors conclude that ultra-high-field MR imaging may be useful in distinguishing MS from neuromyelitis optica.
Tweet from Dr. Zamboni: "Iron-laden plaques at MR bio marker of Multiple Sclerosis vs NMO"
http://www.ajnrblog.org/2016/07/30/iron-non-iron-related-characteristics-multiple-sclerosis-neuromyelitis-optica-lesions-7t-mr/

Editor's Choice: Chawla et al. Iron and Non-Iron-Related Characteristics of Multiple Sclerosis and Neuromyelitis Optica Lesions at 7T MRI