The lab that discovered the brain's lymphatic vessels is now publishing on MS and the brain's meningeal system. I'm just starting to dig into this paper, and am looking forward to more feedback from Jonathan Kipnis....but suffice it to say, the brain's drain is a huge part of #MS in humans. #onward #science https://www.nature.com/articles/s41593-018-0227-9#Sec35

Louveau et al. demonstrate that meningeal lymphatics drain CSF-derived macromolecules and immune cells and play a key role in regulating neuroinflammation. Meningeal lymphatics may represent a new therapeutic target for multiple sclerosis.