Mitochondrial ferritin in neurodegenerative diseases, Neuroscience Research 2013

Highlights
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Mitochondrial ferritin (FtMt) is a novel protein localized to the mitochondria.
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FtMt is expressed in restricted tissues including the brain.
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FtMt lacks iron regulatory elements and its expression is increased by oxidative stress.
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FtMt is increased in the cerebral cortex of AD patients and in the substantia nigra of individuals with PD and RLS.
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The presence of FtMt prevents cell death induced by oxidative stress and neurotoxic proteins.
learn more/full paper: http://www.sciencedirect.com/science/article/pii/S016801021300182X

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