Updates on two studies looking at primary progressive MS....

"High dose Biotin withdrawn from European licensing"
"Medday, the company developing high dose biotin for progressive MS, has told the European Medicines Agency that it wishes to withdraw its licence application for the treatment of progressive multiple sclerosis."
https://www.mstrust.org.uk/news/news-about-ms/high-dose-biotin-withdrawn-european-licensing

"Antidepressant May Help Combat the Course of Multiple Sclerosis" Reported Dec 20 2017
"The team worked with approved drugs, the side effects of which have already been amply documented. From among those drugs, the researchers selected 249 well-tolerated therapeutics that enter the nervous system safely; this is where chronic inflammation occurs in progressive MS. Using cell cultures, they tested which of the 249 substances are capable of protecting nerve cells from the damaging influence of iron. In MS patients, iron is released due to cell damage, damaging nerve cells in turn."
http://neurosciencenews.com/clomipramine-multiple-sclerosis-8218/