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Wednesday, May 18, 2011 6:01 AM | CCSVI in Multiple Sclerosis Volg link

Dr. E. Mark Haacke is another hero who spoke at the Hubbard conference regarding new research.  He continues to refine his protocol and find new ways to compare blood flow in and out of the brains of normals (controls) vs. pwMS and CCSVI.

One means of visualizing this difference is with blood flow quantification.  Measuring the actual speed and volume of blood going into and out of the brain.  Dr Haacke is now teaching other researchers how to do this.  MRV stagnent images of veins may look just fine to researchers...but once flow quantifications are done, it is obvious these veins are NOT NORMAL.

Dr. Haacke discusses this in the YouTube video segment linked here:

http://www.youtube.com/user/HubbFound?blend=7&ob=5#p/u/7/8QpxR1nHOIg

six minutes in....

"I believe Zivadinov's work only used the magnitude images, he did not use flow quantification. Now,  I can happily tell you that Robert just sent several of his people to spend time with us a few weeks ago and learn how to do flow quantification so they will be adding this to their future studies....

We can get the cross-sectionals for every vessel...we can calculate the total cardiovascular input into the brain and the venous out put from the brain.  Here's a case of normals,  where we're looking at the major veins, they flow at about 10cm per second.  They don't have these wild swings associated with them.  Here's a case.... all four of the major veins in this individual have come to almost zero or reflux flow, and so because of that, in order to get that blood out, talk about a stress on your system, the flow has to double in the 2nd half of the cardiac cycle and becomes 20 cm per second in order to get it out.   I've actually seen flow as high as 60 cm per second in an MS case because of this type of problem."

0 cm. of blood on this first half of the cardiac cycle, then 20cm on the second half.  60 cm of blood in a pwMS.  This is NOT NORMAL. 

Thanks, Dr. Haacke.  It is because of your relentless search for the truth of cerebral bloodflow differences in those with MS and normal people, that we can trust the real story will continue to be illucidated.