Time for good news/bad news about the upcoming European Committee for Treatment and Research in Multiple Sclerosis conference.
The good news: There are more posters, abstracts and presentations on CCSVI than ever before. And many of them show positive associations with MS and CCSVI.
The bad news: Anti-CCSVI neurologists are digging in their heels.
One example is Dr. Giancarlo Comi, the very vocal opponent of CCSVI research in Italy, who began his own 50+ multi-center doppler studies (COSMO) after removing Dr. Zamboni's doppler protocol. These studies are being funded by the Italian MS Society, of which Dr. Comi is the lead consulting neurologist. If last year's ECTRIMS conference was any indication, we can expect lots of bluster, theatrics and negative findings from Dr. Comi and his crew. More information on the COSMO doppler studies in Italy and Dr. Comi's very long list of pharmaceutical relationships--
link to COSMO study information
Another interesting presentation to note is Kuwaiti neurologist Dr. Alroughani, making a presentation on the Kuwaiti CCSVI study, without bringing the IRs along. He tried this last year at AAN, but his presentation and abstract were removed, due to a public outcry from the Kuwaiti IR team. He's ba-a-a-ck....
Endovascular treatment of chronic cerebro-spinal venous insufficiency in multiple sclerosis: a retrospective study
R. Alroughani, S. Lamdhade (Kuwait, KW)
Here's what happened last year, when Dr. Alroughani wrote up his impressions of the Kuwaiti study and tried to present it at the AAN conference.
open letter to AAN from Kuwaiti CCSVI team
Here is the compete list of CCSVI related information at ECTRIMS. I will get the abstracts up and added to this note as they are made available.
Thursday, October 11, 2012
15:30 - 17:00
Poster Session 1
Chronic cerebro-spinal venous insufficiency (CCVI)Multiple stenosis or multiple sclerosis?
P 624 G. Panczel, C. Rozsa, K. Kovacs, I. Szikora, Z. Berentei, I. Gubucz, M. Marosfoi, A. Rozsa (Budapest, HU)
The prevalence of incidental findings in multiple sclerosis patients and control subjects evaluated for possible chronic cerebrospinal venous insufficiency: Do multiple sclerosis researchers report incidental findings?
P 625 . Trufyn, J. Scott, J. Modi, M. Goyal, D. Lautner, D. Bhayana, J. Davenport, J. Mah, J.M. Burton, M.D. Hill, F. Costello (Calgary, CA)
British Columbia CCSVI Registry: preliminary survey resultsI
. Yee, A. Traboulsee, A. Sadovnick, L. Machan (Vancouver, CA)
Hydration status may confound CCSVI ultrasound assessment
C. Diaconu, R. Fox, M. Lu, A. Grattan, A. Rae-Grant, H. Gornik, S. Kim (Cleveland, US)
Prospective, case-control study of CCSVI with imaging-blinded assessments P 628
J. Wolinsky, L. Kramer, A. Barreto, A. Cohen, S. Brod, T.-T. Bui, P. Narayana, J. Jemelka, F. Nelson, J. Lindsey (Houston, US)
Endovascular treatment of chronic cerebro-spinal venous insufficiency in multiple sclerosis: a retrospective study
R. Alroughani, S. Lamdhade (Kuwait, KW)
Intra and extra cranial arterial, venous and CSF analysis comparing MS patients and healthy controls
S. El Sankari, O. Balédent, V. van Pesch, T. Duprez, C. Sindic (Bruxelles, BE; Amiens, FR)
Anatomical cadaver study of the internal jugular veins' configuration in non-MS persons
M. Denislic, M. Zorc, Z. Milosevic, O. Mendiz, R. Zorc Pleskovic, D. Ravnik (Ljubljana, SI; Buenos Aires, AR)
Comparison of intravascular ultrasound to gold standard catheter venography for detection of extra-cranial venous abnormalities indicative of CCSVI: results of the PREMiSe (Prospective Randomized Endovascular therapy in Multiple Sclerosis) study
R. Zivadinov, B. Weinstock-Guttman, K. Dolic, C. Kennedy, K. Marr, V. Valnarov, A. Siddiqui (Buffalo, US)
Heart disease, overweight and cigarette smoking are associated with increased prevalence of extra-cranial venous abnormalities
K. Dolic, B. Weinstock-Guttman, K. Marr, V. Valnarov, E. Carl, J. Hagemeier, C. Kennedy, C. Kilanowski, D. Hojnacki, M. Ramanathan, R. Zivadinov (Buffalo, US)
Cine cerebrospinal fluid imaging changes in patients with multiple sclerosis after venous angioplasty. A 1-year follow-up study
R. Zivadinov, C. Magnano, R. Galeotti, C. Schirda, B. Weinstock-Guttman, E. Menegatti, J. Hagemeier, A.M. Malagoni, D. Hojnacki, C. Kennedy, I. Bartolomei, C. Beggs, F. Salvi, P. Zamboni (Buffalo, US; Ferrara, IT; Bologna, IT; Bradford, UK)
Cerebrospinal venous outflow in MS patients and fatigue/depression
E.L.J. Hoogervorst, S.C. Tromp, S.T.F.M. Frequin (Nieuwegein, NL)
Friday, October 12, 2012
10:00 - 10:15
Platform presentation of selected abstracts on therapy and clinical trials (Amphitheatre)Endovascular treatment of CCSVI in patients with multiple sclerosis: clinical outcome of an Italian cohort of 462 cases
A. Ghezzi, P.O. Annovazzi, M.P. Amato, R. Balgera, P. Banfi, M. L. Bartolozzi, R. Bergamaschi, A. Bertolotto, A. Bianchi, A Bosco, E. Capello, M. Capobianco, R. Capra, P. Cavalla, R. Clerici, G. Coarelli, E. Cocco, N. De Rossi, C. Di Tillio, M.T. Ferrò, A. Gallo, P. Gallo, L. Lamantia, A. Lugaresi, G. Lus, S. Malucchi, L. Moiola, L. Provinciali, F. Patti, P. Perini, P. Perrone, A. Protti, M.E. Rodegher, P. Rossi, M. Rottoli, M. Rovaris, G. Salemi, M. Salvetti, I. Simone, M.R. Tola, M. Trojano, F. Vitetta, M.G. Marrosu, G. Comi and MS Study Group, Italian Society of Neurology
15:30 - 17:00
Chronic cerebro-spinal venous insufficiency (CCVI)
Prevalence, sensitivity and specificity of chronic cerebrospinal venous insufficiency in other neurologic diseases. A case-control study R. Zivadinov, K. Marr, V. Valnarov, C. Kilanowski, C. Kennedy, T. Guttuso, D. Lichter, N. Silvestri, L. Fugoso, E.A. Yeh, M. Ramanathan, R. Benedict, E. Carl, D. Hojnacki, B. Weinstock-Guttman (Buffalo, US)
15:30 - 17:00
Chronic cerebro-spinal venous insufficiency (CCVI) A prospective follow-up of the venous haemodynamics in patients with MS: the fluctuating natural course of CCSVI
L.H. Visser, L. van den Berg, A. van der Zande, G. van den Berg, B. Westerhuis (Tilburg, Maassluis, NL)
15:30 - 17:00
Chronic cerebro-spinal venous insufficiency (CCVI) Prevalence, sensitivity and specificity of chronic cerebrospinal venous insufficiency in paediatric multiple sclerosis
R. Zivadinov, E.A. Yeh, K. Marr, V. Valnarov, C. Kilanowski, M. Karpinski, E. Carl, C. Kennedy, B. Weinstock-Guttman (Buffalo, US)
Chronic cerebro-spinal venous insufficiency (CCVI) A systematic review of the association between chronic cerebrospinal venous insufficiency and multiple sclerosis J.M. Burton on behalf of the Canadian CCSVI Systematic Review Group
Chronic cerebro-spinal venous insufficiency (CCVI) cerebrospinal venous insufficiency in MS/CIS is not consistently observed with a blinded ultrasound protocol K. Knox, J. Gitlin, S. Harvey, C. Hayward, S. Wiebe, C. Voll, P. Szkup, R. Otani (Saskatoon, CA)
Chronic cerebro-spinal venous insufficiency (CCVI)A prospective study comparing ultrasonography and angiography of internal jugular veins in multiple sclerosis patients
M. Simka (Katowice, PL)
Chronic cerebro-spinal venous insufficiency (CCVI)Chronic cerebrospinal venous insufficiency and extracranial venous stenoses in Danish multiple sclerosis patients M. Blinkenberg, P. Åkeson, H. Sillesen, S. Lövgaard, F. Sellebjerg, O.B. Paulson, H.B. Siebner, P.S. Sørensen (Copenhagen, DK)
Chronic cerebro-spinal venous insufficiency (CCVI) Cerebral venous outflow in multiple sclerosis studied by transcranial brain photoplethysmography
S. Viola, P. Viola, P. Litterio, M.P. Buongarzone, L. Fiorelli (Vasto, Atessa, IT)
Diagnosis and differential diagnosis A Pilot Reproducibility Evaluation of CoSMo Study (PREP Study): methodological aspects
G Malferrari, M.L. Zedde, S. Sanguigni, D. Ciampanelli, P. Prati, C. Baracchini, N. Carraro, M. Del Sette, E. Stolz, L. Motti, G. Comi, G. Mancardi, M.A. Battaglia on behalf of CoSMo Study
Chronic cerebro-spinal venous insufficiency (CCVI)No evidence for impairment in venous haemodynamics in children or young adults with paediatric-onset multiple sclerosis
B. Banwell, S. Laughlin, J. Traubici, S. Khan, K.Y. Chan, R.A. Marrie, C.K. Macgowan (Toronto, Winnipeg, CA)
Saturday, October 13, 2012
08:45 - 09:00
Late Breaking News II (Forum 2 & 3)
Chronic Cerebro-Spinal Venous Insufficiency (CCSVI) and global venous haemodynamics in multiple sclerosis: the CoSMo study G. Comi, M.A. Battaglia, A. Bertolotto, M. Del Sette, A. Ghezzi, G. Malferrari, M. Salvetti, M. Sormani, E. Stolz, L. Tesio, G.L. Mancardi on behalf of the CoSMo study group
