In 2008 Dr. Paolo Zamboni of Ferrara, Italy discovered a link between

chronic cerebro-spinal venous insufficiency (CCSVI) and Multiple

Sclerosis (MS). His discovery came as a personal mission- to cure his

wife as she began a downward spiral after her diagnosis.

Reading everything he could on the subject, Dr. Zamboni found decades of

old research citing excess iron as a possible cause of MS. He started

his research of how a buildup of iron was somehow damaging blood vessels

in the brain as these decades of previous research had suggested.

Setting forward the theory that many types of MS are actually caused by a

blockage of pathways that remove excess iron from the brain- and by

simply clearing out a couple of major veins (jugular and azygos).

Re-opening the blood flow, the root cause of the disease can be

eliminated.

With a Color Doppler Ultrasound machine, he made the staggering

discovery that his wife had vein malformation. He immediately scheduled

her for just a simple balloon angioplasty to unblock the veins. He went

on to test 65 patients with MS and discovered that more than 90% of them

had have some form of venous malformation or blockage in the veins that

drain blood from the brain. In three years proceeding her procedure his

wife has not had another debilitating MS attack.

Roughly 3,000 MS patients from all over the world have been,

successfully, treated for CCSVI. That number continues to grow daily as

treatment clinics in 47 countries have wait lists that are booked

through the year 2012. Hundreds of suffering American and Canadian

patients are seeking treatment overseas and in Mexico because they can’t

have the simple angioplasty performed in the United States, nor in

Canada.

Multiple sclerosis has never been proven to be a neurological, nor an

auto-immune disease. Yet big pharma continues to make an estimated $10

Billion in MS drug sales per year. About $75 thousand per patient, per

year. Even though now, thanks to Dr. Zamboni, it is published research

and proven a vascular disease.

Chronic cerebrospinal venous insufficiency... it’s a chronic (ongoing)

problem where blood from the brain and spine has trouble getting back to

the heart. It’s caused by stenosis (a narrowing) in the veins that

drain the spine and brain. Blood takes longer to get back to the heart,

and it can reflux back into the brain and spine or cause edema and

leakage of red blood cells and fluids into the delicate tissue of the

brain and spine.

Blood that stays in the brain too long creates “slowed perfusion”...a

delay in deoxygenated blood leaving the head. This can cause a lack of

oxygen (hypoxia) in the brain. Plasma and iron from blood deposited in

the brain tissue are also very damaging.

Another important observation made by Zamboni's team is that the pattern

of reflux, that is, the specific pathway the blood uses to flow back to

the brain, showed a strong correlation to the type of MS. Persons with

PPMS had a different reflux pattern that those with RRMS and SPMS.

Furthermore, the PPMS reflux pattern provided a good explanation why this form of MS is more aggressive and problematic.

Multiple Sclerosis being a vascular disease is NOT a new theory- TIMELINE...

1863 Dr. E. Rindfleisch noticed that, consistently in all the autopsy

specimens of MS brains he viewed with his microscope, a vein engorged

with blood was present at the centre of each lesion.

1930s Dr. T. J. Putnam researched lesions and noted that thrombosis of

small veins could be the underlying mechanism of plaque formation.

1942 Dr. Robert Dow and Dr. George Berglund continue with Dr. Putnam's research in finding venous connections to MS lesions.

Top ?

1950 Dr Zimmerman and Netsky carry on with Dow and Berglund's research,

and note that the lesions are indeed venous in nature, but not caused by

small thrombosis as Putnam surmised.

1960s Dr. Torben Fog, a Danish professor noted that MS lesions are

predominantly around the small veins. His subsequent study of 51 plaques

from two cases of typical MS, making thin sections of the plaques and

following their shape and course with direct drawings of each section,

showed that most were prolongations of per ventricular plaques, and that

the plaques did follow the course of the venous system.

1970s Dr. F. Alfons Schelling. In 1973,at the University of Innsbruck,

when F. Alfons Schelling, M.D. began investigations into the causes and

consequences of the enormous individual differences in the widths of the

venous outlets of the human skull. The results of this study appeared,

in 1978, in the official organ of the German-speaking Anatomical

Societies, the "Anatomischer Anzeiger".

2008 Dr. Paolo Zamboni. With his team of researchers, Dr. Zamboni

presented academic papers showing a unique similarity (dubbed CCSVI) in

100 percent of MS patients they studied. The vascular connection to MS

was studied back in the 1950's and it was proven false. Back then,

specialists attempted the use of blood thinners to treat MS and it could

not resolve the venous stenosis issue, Dr Zamboni found in all of the

patients he tested. The advancement in technology has proven the

difference.

2009 Testing and treatment begins in several countries, not United States nor Canada.

2010 47 countries testing and treating, trials available in the United States.

References:

Rindfleisch E. - "Histologisches detail zu der grauen degeneration von gehirn und ruckenmark". Archives of Pathological Anatomy and Physiology. 1863;26:474–483

Putnam, T.J. (1937) Evidence = of vascular occlusion in multiple sclerosis

VASCULAR PATTERN OF LESIONS OF MULTIPLE SCLEROSIS Arch Neurol Psychiatry. 1942;47(1):1-18

Zimmerman, H. M., Netsky, M. G.: The pathology of multiple sclerosis. Res. Publ. Ass. Nerv. Ment. Dis. New York 28, 271--312 (1950)

Fog Torben, The topography of plaques in multiple sclerosis, with special reference to cerebral plaques. Acta Neurol Scand, 41,Suppl. 15:1, 1965) Fog T. On the vessel-plaque relations in the brain in

multiple sclerosis.ActaPsychiat Neurol Scand. 1963; 39, suppl. 4:258

http://myliberationtreatment.com/CCSVI/info-on-ccsvi-surgery.html