We had a wonderful day at our conference on a beautiful weekend in San Diego. We had some technical difficulties with the skype presentations (Drs Zamboni, Dake and McGuckin) but the rest of the day was filled with a lot of wonderful information. Thanks to all who attended and a special thanks to those who donated to the Hubbard Foundation to help us continue to support research and education.
David Hubbard discussed the Hubbard Foundation’s clinical outcomes study. 260 Patients pre and post venoplasty statistically significant using the MSIS.
66% overall improvement
The more sites treated the better the outcome
SPMS did less well that PPMS and RRMS
Duration of disease…no difference
Age, no difference
Women did better than men
Diet and lifestyle needs to be evaluated.
Pathogenesis: auto immune?
Decreased IJ flow?
CNS venous reflux?
Hypoperfusion?
CNS venous inflammation?
Oligodendrocytes die first and white cells enter later
fMRI…movie of the brain
BOLD venous test….”tell time” test…looking at the function of several areas of the brain.pre venoplasty MS patients have less brain blood flow.
After venoplasty the brain blood flow normalizes.
Changes in the surging of blood in the brain occur the day after venoplasty.
This cannot be placebo
Flow of fluid through the brain improves the day after venoplasty(perfusion)
Every year when a person with MS has an MRI they should also have MRV and perfusion.
Skype presentations:
Dr Dake
Valves in the veins
CCSVI is associated with stenosis and or occlusions of the jugular and or azygos veins
Collateral venous drainage
Reduced cerebral blood flow
Ccsvi is dx’d with duplex ultrasound or MRV
Where do the venous obstruction occur?..Not just in IJV and azygos but elsewhere. Some can be intrinsic some extrinsic. Often the valve is involved.
Who has valves?
Bipeds, quadrupeds and mammals
Where are the valves?
Head and neck
Dural sinuses and tributaries have no valves
Emissary veins joining the superior sagittal sinus to the scalp have valves
IJV and its affluents have valves
The hemiazygos and venous plexus of the vertebral column and spinal cord have no valves.
Iliac veins have no valves.
There are different valves
IJV there is one valve at the junction of the subclavian
Why do we need valves?
Valves very rarely close
Effects of external muscular compression of a venous plexus. Valves exist to give direction to the blood stream and facilitate its regular dispersion, especially during muscular activity.
What can go wrong?
The valve can be inverted,incomplete or in an abnormal area.
Dr Fox
Evaluated actual veins only 2 abnormalites in Normals, more in pwMS
Dr McGuckin
FDA letter has gone out regarding CCSVI
We need randomized controlled trials
Hubbard foundation’s registry has been instrumental in collecting data on pwMS.
Every pt in our study has had abnormal valvular structures.
Left renal vein has been involved in most patients who did not have a response and when treated the patients got better.
Angioplasty balloons are not approved for veins yet most IR’s have been using them for venous stenosis for years for dialysis.
In person presentations
Don Ponec,
Outcomes and complications in CCSVI treatment:
FDA alert warning patients to make informed decisions
SIR made recommendations that IR’s speak to patients about that fact that the treatment is not proven, that there can be adverse events.
Discussed the hx of the CCSVI theory
The MS community is very activist as a community
50% of IRs believe in CCSVI and 88% of IR’s would have the tx if they had MS
MS is difficult disease in which to assess outcomes
Placebo arm of many drug trials have up to a 60% response rate.
Complications are difficult to assess
The SIR, a yr ago created guidelines for CCSVI tx
Problems with treating ccsvi
We don’t know for sure what we are treating
We don’t know for sure how to treat it
Other than that, we have it all figured out
Controversies in CSVI
Diagnostic/venographic criteria are not well defined
No consensus on what is a significant finding
Too much hyperbole on the web
The treatment is very safe
Very high incidence of venous abnormalities in MS
Without major funding assessing clinical outcomes will be difficult
Need to seek an IDE and do a randomized trial.
DR John Cooke introduced by Joan Beal
Wrote the book Cardiovascular Cure
How the blood vessels and blood effect of MS
Joan wrote to Dr Cooke, and she sent him Dr Zamboni’s paper Dr Cooke read DR Z’s paper and took it to Dr Dake who performed the venoplasty on Jeff. Her husband was treated 3years ago using a holistic approach. His grey matter, by MRI has improved:
Dr Cooke,
Venous angioplasty and stenting reduced fatigue symptoms for 1year. Not a randomized trial.
Endothelium…lining of blood vessel
Hypothesis altered cerebrovenous hemodynamics in ccsvi predispose to ms pathobiology
Alteration in hemodynamic can cause permeability to the endothelium
Thickening of vessel wall. Perivenular cuffing infiltration of inflammatory cells, RBC egress and hemosiderin deposition
The endothelium maintains vascular homeostasis it is the Teflon coating of our blood vessels.
Release NO which causes vasodilation. Blood vessels can adapt to flow and regulate its diameter. The blood flow is entirely dependent on the endothelium. The endothelium can sense changes in the blood flow.
Disturbed flow happens at bends, branches and bifurcations.
Endothelial biology is altered by flow patterns
Role of endothelial adhesion molecules and disturbed flow. If you have disturbed venous flow the endothelium becomes more adhesive(like Velcro) and sets the person up for inflammation.
Ccsvi causes abnormal venous flow
External compression of a blood vessel can cause disturbed blood flow
Ccsvi changes venous flow and pressure and effects the endothelium and causes the endothelium to become like Velcro. This becomes attractive to white blood cells and causes inflammation.
Has submitted grants to NIH et al and has been turned down for CCSVI.
Changes in flow can change the endothelium. The endothelium in the brain is very different than the endothelium elsewhere…it’s very tight
Needs funding for more animal models.
Can diet help the endothelium? Not sure but omega 3, micronutrients helps with arteries, but we haven’t studied the veins
Greg Berkoff, DC…one chiropractic Perspective
Upper cervical spine manipulation…is it a viable treatment option?
If upper cervical spine manipulation does help with ms then CCSVI might give a reason for why it works.
thereS a network of veins in, and around the 1st cervical vertebra. The vertebral plexus works selectively when we are upright
verterbral system is just as important as the internal jugular system.
All the veterbral veins develop in the upper cervical vertabra
Manual traction which can be sustained can provide decompression.
Looked at 1 pt and 4 normals to see if traction can increase flow. Traction applied before, MR venogram, and after venogram
Flow increases after traction
Pt with MS…flow -7.02 ,after traction -9.24 almost a 30% increase of flow(below 8 is abnormal)
Tractioning of the cervical spine may be a viable treatment for ccsvi
Dr Wahls (asked not be be videoed)
Minding my mitochondria
Wahls diet recommends 9 cups of fruit and veggies per day
“ Superior docs prevent disease
Mediocre docs treat impending disease
Poor docs treat disease”
Over time with MS brains and spinal cords start to shrink. She did pub med research (Willett, WC. Science, 2002:296, 695-697)
Balancing lifestyle and genomics research for disease prevention
It’s not the fault of your DNA that you become ill.
The environment is much more important than the genetics.
Fish oil, creatine, and coQ10. The mitochondria in all the neurodegenerative diseases are dying. It’s the power supply of the cell
She started experimenting with the supplements. And her fatigue was dissaptaing. Started adding more nutrients.
www.functionalmedicine.org
took a course on neuroprotection a functional medicine approach for common and uncommon neurologic syndromes.
Environmental factors
Genetic interaction with environment
vascular problems
Nutrition/vit d
Toxins/smoking
Stress hormone excess
Allergies sensitivities
Exercise
Family connections
Purpose in life
Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging. Study looking at plasma values of b vit vit d and e vitamins, greens sulfur, color, grass fed meat organ meats had better cognitive scores and more brain tissue
85% did well
lower cognitive score and less brain tissue
high transfat
hydrogenated fats and heated vegetable oils
published in Neurology 2012 Jan 24;78
Myelin +=insulation for wiring
Vit b1B9 b12 omega 3 fatty acids and iodine,
Neurotransmitters Sulfur…B6
Bourre jm effects of nutrients in food on the structure and function of the nervous sys.
J Nutr Health aging 2006;
B vitamins, sulfur, antioxidants
Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, alzheimers disease and parkinsons disease
Vascular health and health disease
Too much inflammation
Clogging of arteries and veins
Consequence of blockages
Arteries ,,,heart disease/stroke
Venous-ccsvi
Intensive lifestyle changes for reversal of coronary heart disease. JAMA 1998 Dec 16
Blood viscosity and MS too much inflammation
MS blood is thicker
If you eat a lot of white flour high fructose corn syrup and sugar….inflammation
Lots of sulpher and beets and greens and berries protect blood vessels
Garlic, onions and kale and chives influences endothelial health and the viscosity of the blood.
Hunter gatherer diet is the healthiest
She took the nutrients that were important to her brain and she designed a food plan to get those nutrients
Dinner plate is 3 cups of veggies…greens rich in BACK (B12 requires animal protein)vit k is important for endothelial health, need minerals for the vitamins to help.
Sulphur supports brain
Cabbage, onion and mushrooms +sulfur
Colors=flavonoids, antioxidants, retinas mitochondria and toxin removal
Wild fish= rich in omega 3 fatty acid= myelin and straight teeth
Myelin and straight teeth…grass fed meat and organ meats+ coQ10, vitamins, minerals,
2-3xper week
liver has more vit and minerals than broccoli
seaweed= iodine which helps with myelin and toxin removal and decreases cancer
food allergies are hard to diagnose.
Gluten sensitivity and brain diseases
Celiac, gluten ataxia, gluten encephalopathy, autism, ALS, seizures
Dairy free casein is a cause of sensitivity esp if you are gluten sensitive.
Mitochondria-inflammation issue
Depression, bipolar, anxiety, ocd, eating disorder, dementia, learning disability, autism, schizophrenia, hypertension, DM, arthritis,
Ann Boroch
Healing ms with nutrition and detoxification
Inflammation and infection is what causes the problems
Read Dr Cooks book on the yeast connection
She gave up gluten, alcohol and sugar.
If you don’t maintain balance the yeast comes back worse
Candida diet again and took Nystatin and removed her fillings.
17years of symptom free
what creates ms
inflammation and infection environment, GI problems, diet, infections,
Everyone with MS has candida and virus. The genes turn on because of the environment. If some of it goes to the nervous sys you have ms. If it goes to the muscles you have fibromyalgia
Candida most grossly ignored microorganism in western medicine, yeast/fungal toxins disrupt communication of the body. Antibiotics, steroids, chemo, HRT, sugar stress and alcohol
Infection…antibiotics…destroy good and bad bacteria in the GI tract…candida overgrowth…toxins from yeast and fungus weaken the immune system.
Maldigestion, malabsorption, leaky gut, compromised liver function, weakened immune system compromised BBB, autoimmune disease, Alzheimer, cancer, and other chronic progressive conditions. The endothelium gets leaky. Yeast overgrowth decreases communication in the body. Remove infection and inflammation.
Takes diligence and commitment are essential. The loss of intestinal barrier function is necessary to develop autoimmunity.
Link between candida and ms
Dr perlmutter the frequency of focal white matter lesions in pts with inflammatory bowel disease is almost as high as those in pts with ms. These findings provide convincing evidence supporting that relationship.
Environmental toxicity in our air, water, xenoestrogens (pcb, bpa, phthalates)
Vaccination, cell phone, cordless phone, tv and computers,
Noise pollution
Recommendation to neutralize environmental toxicity
Ionic foot baths, air purifier, water system or bottled water company, use speaker function when talking on cell , non toxic cleaning products.
STRESS:
Ability to handle emotional mental and physical demands of life, we all have stress , stress and fear are the number one body breakers, stress increases cortisol secreted by the adrenal glands, which inflames the body,
How to turn this around
Candia diet, detoxify and manage stress
Detoxification:
Supplements probiotics, vit c3, e c coQ10 b12, evening primorose oil,oregano oil, n- acetyl cysteine, turmeric resveratrol
Dr Chaudhary(neurologist and Ayurvedic doctor(Devin’s doctor)
Ayurvedic perspective on MS
Moving forward sometimes mean looking backward
“Science of life” ancient medical system of India, 5,000year old
objective to prolong life and promote perfect health
to completely eradicate disease and dysfunction of the body
you can reverse and irradicate disease
5 basic elements in the form of dosha
vata, pitta, kapha
MS pts are mostly vata or pitta
Everyone has these elements and are usually a combination. Many things can disturb the natural balance of the doshas, stress, unhealthy diet or routine, weather, the disturbance shows up as disease
Ayurvedic docs prescribe holistic, multi modality tx programs to bring the doshas back into balance.
A specialized ayurvedic hx and exam
Pulse diagnosis
There is a link between the GI tract and the nervous system the ayurvedic tx is 80% diet.
the underlying pattern of imbalance at the basis of current or future disease
the patients constitutional type or mind body type
vata
governs bodily functions concerned with mvmt main imbalance in MS
blood circulation, breathing, elimination, heartbeat
space and wind
pitta
governs bodily functions concerned with heat and temp control
pitta people are type A
sharp mentally have mildest form of ms if you can get under control
kapha
muscle, fat , bone, joints
multi modality therapeutic approach
diet and nutrition, herbs, meditation, breathing exercises, daily self massage with herbalized oil, yoga, seasonal purification procedures
NO MS PATIENTS HAVE NORMAL DIGESTION
Digestive tea Recipe
Boil 4-5 cups of water in the morning.
Add ½ tsp of the following seeds to the water and continue to let steep for at least 10 min with the lid on.
.whole cumin seeds
.whole coriander seeds
.whole fennel seeds
Strain out the seeds and pour the liquid into a thermos. Sip the liquid throughout the day. Start fresh with a new batch of tea each morning. If the tea is too strong or if you experience some initial discomfort, reduce the amount of the seeds to ¼ tsp for 2 weeks and then increase it back to ½ tsp
Fred Fox IRB and importance of collecting data
Discussed the FDA warning and the need for docs to get IDE to continue to study CCSVI and treat.
We had a yummy gluten free lunch and after the conference we had a gluten free reception with delicious snacks.
Hubbard Foundation conference May 12, 2012
We had a wonderful day at our conference on a beautiful weekend in San Diego. We had some technical difficulties with the skype presentations (Drs Zamboni, Dake and McGuckin) but the rest of the day was filled with a lot of wonderful information. Thanks to all who attended and a special thanks to those who donated to the Hubbard Foundation to help us continue to support research and education.
David Hubbard discussed the Hubbard Foundation’s clinical outcomes study. 260 Patients pre and post venoplasty statistically significant using the MSIS.
66% overall improvement
The more sites treated the better the outcome
SPMS did less well that PPMS and RRMS
Duration of disease…no difference
Age, no difference
Women did better than men
Diet and lifestyle needs to be evaluated.
Pathogenesis: auto immune?
Decreased IJ flow?
CNS venous reflux?
Hypoperfusion?
CNS venous inflammation?
Oligodendrocytes die first and white cells enter later
fMRI…movie of the brain
BOLD venous test….”tell time” test…looking at the function of several areas of the brain.pre venoplasty MS patients have less brain blood flow.
After venoplasty the brain blood flow normalizes.
Changes in the surging of blood in the brain occur the day after venoplasty.
This cannot be placebo
Flow of fluid through the brain improves the day after venoplasty(perfusion)
Every year when a person with MS has an MRI they should also have MRV and perfusion.
Skype presentations:
Dr Dake
Valves in the veins
CCSVI is associated with stenosis and or occlusions of the jugular and or azygos veins
Collateral venous drainage
Reduced cerebral blood flow
Ccsvi is dx’d with duplex ultrasound or MRV
Where do the venous obstruction occur?..Not just in IJV and azygos but elsewhere. Some can be intrinsic some extrinsic. Often the valve is involved.
Who has valves?
Bipeds, quadrupeds and mammals
Where are the valves?
Head and neck
Dural sinuses and tributaries have no valves
Emissary veins joining the superior sagittal sinus to the scalp have valves
IJV and its affluents have valves
The hemiazygos and venous plexus of the vertebral column and spinal cord have no valves.
Iliac veins have no valves.
There are different valves
IJV there is one valve at the junction of the subclavian
Why do we need valves?
Valves very rarely close
Effects of external muscular compression of a venous plexus. Valves exist to give direction to the blood stream and facilitate its regular dispersion, especially during muscular activity.
What can go wrong?
The valve can be inverted,incomplete or in an abnormal area.
Dr Fox
Evaluated actual veins only 2 abnormalites in Normals, more in pwMS
Dr McGuckin
FDA letter has gone out regarding CCSVI
We need randomized controlled trials
Hubbard foundation’s registry has been instrumental in collecting data on pwMS.
Every pt in our study has had abnormal valvular structures.
Left renal vein has been involved in most patients who did not have a response and when treated the patients got better.
Angioplasty balloons are not approved for veins yet most IR’s have been using them for venous stenosis for years for dialysis.
In person presentations
Don Ponec,
Outcomes and complications in CCSVI treatment:
FDA alert warning patients to make informed decisions
SIR made recommendations that IR’s speak to patients about that fact that the treatment is not proven, that there can be adverse events.
Discussed the hx of the CCSVI theory
The MS community is very activist as a community
50% of IRs believe in CCSVI and 88% of IR’s would have the tx if they had MS
MS is difficult disease in which to assess outcomes
Placebo arm of many drug trials have up to a 60% response rate.
Complications are difficult to assess
The SIR, a yr ago created guidelines for CCSVI tx
Problems with treating ccsvi
We don’t know for sure what we are treating
We don’t know for sure how to treat it
Other than that, we have it all figured out
Controversies in CSVI
Diagnostic/venographic criteria are not well defined
No consensus on what is a significant finding
Too much hyperbole on the web
The treatment is very safe
Very high incidence of venous abnormalities in MS
Without major funding assessing clinical outcomes will be difficult
Need to seek an IDE and do a randomized trial.
DR John Cooke introduced by Joan Beal
Wrote the book Cardiovascular Cure
How the blood vessels and blood effect of MS
Joan wrote to Dr Cooke, and she sent him Dr Zamboni’s paper Dr Cooke read DR Z’s paper and took it to Dr Dake who performed the venoplasty on Jeff. Her husband was treated 3years ago using a holistic approach. His grey matter, by MRI has improved:
Dr Cooke,
Venous angioplasty and stenting reduced fatigue symptoms for 1year. Not a randomized trial.
Endothelium…lining of blood vessel
Hypothesis altered cerebrovenous hemodynamics in ccsvi predispose to ms pathobiology
Alteration in hemodynamic can cause permeability to the endothelium
Thickening of vessel wall. Perivenular cuffing infiltration of inflammatory cells, RBC egress and hemosiderin deposition
The endothelium maintains vascular homeostasis it is the Teflon coating of our blood vessels.
Release NO which causes vasodilation. Blood vessels can adapt to flow and regulate its diameter. The blood flow is entirely dependent on the endothelium. The endothelium can sense changes in the blood flow.
Disturbed flow happens at bends, branches and bifurcations.
Endothelial biology is altered by flow patterns
Role of endothelial adhesion molecules and disturbed flow. If you have disturbed venous flow the endothelium becomes more adhesive(like Velcro) and sets the person up for inflammation.
Ccsvi causes abnormal venous flow
External compression of a blood vessel can cause disturbed blood flow
Ccsvi changes venous flow and pressure and effects the endothelium and causes the endothelium to become like Velcro. This becomes attractive to white blood cells and causes inflammation.
Has submitted grants to NIH et al and has been turned down for CCSVI.
Changes in flow can change the endothelium. The endothelium in the brain is very different than the endothelium elsewhere…it’s very tight
Needs funding for more animal models.
Can diet help the endothelium? Not sure but omega 3, micronutrients helps with arteries, but we haven’t studied the veins
Greg Berkoff, DC…one chiropractic Perspective
Upper cervical spine manipulation…is it a viable treatment option?
If upper cervical spine manipulation does help with ms then CCSVI might give a reason for why it works.
thereS a network of veins in, and around the 1st cervical vertebra. The vertebral plexus works selectively when we are upright
verterbral system is just as important as the internal jugular system.
All the veterbral veins develop in the upper cervical vertabra
Manual traction which can be sustained can provide decompression.
Looked at 1 pt and 4 normals to see if traction can increase flow. Traction applied before, MR venogram, and after venogram
Flow increases after traction
Pt with MS…flow -7.02 ,after traction -9.24 almost a 30% increase of flow(below 8 is abnormal)
Tractioning of the cervical spine may be a viable treatment for ccsvi
Dr Wahls (asked not be be videoed)
Minding my mitochondria
Wahls diet recommends 9 cups of fruit and veggies per day
“ Superior docs prevent disease
Mediocre docs treat impending disease
Poor docs treat disease”
Over time with MS brains and spinal cords start to shrink. She did pub med research (Willett, WC. Science, 2002:296, 695-697)
Balancing lifestyle and genomics research for disease prevention
It’s not the fault of your DNA that you become ill.
The environment is much more important than the genetics.
Fish oil, creatine, and coQ10. The mitochondria in all the neurodegenerative diseases are dying. It’s the power supply of the cell
She started experimenting with the supplements. And her fatigue was dissaptaing. Started adding more nutrients.
www.functionalmedicine.org
took a course on neuroprotection a functional medicine approach for common and uncommon neurologic syndromes.
Environmental factors
Genetic interaction with environment
vascular problems
Nutrition/vit d
Toxins/smoking
Stress hormone excess
Allergies sensitivities
Exercise
Family connections
Purpose in life
Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging. Study looking at plasma values of b vit vit d and e vitamins, greens sulfur, color, grass fed meat organ meats had better cognitive scores and more brain tissue
85% did well
lower cognitive score and less brain tissue
high transfat
hydrogenated fats and heated vegetable oils
published in Neurology 2012 Jan 24;78
Myelin +=insulation for wiring
Vit b1B9 b12 omega 3 fatty acids and iodine,
Neurotransmitters Sulfur…B6
Bourre jm effects of nutrients in food on the structure and function of the nervous sys.
J Nutr Health aging 2006;
B vitamins, sulfur, antioxidants
Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, alzheimers disease and parkinsons disease
Vascular health and health disease
Too much inflammation
Clogging of arteries and veins
Consequence of blockages
Arteries ,,,heart disease/stroke
Venous-ccsvi
Intensive lifestyle changes for reversal of coronary heart disease. JAMA 1998 Dec 16
Blood viscosity and MS too much inflammation
MS blood is thicker
If you eat a lot of white flour high fructose corn syrup and sugar….inflammation
Lots of sulpher and beets and greens and berries protect blood vessels
Garlic, onions and kale and chives influences endothelial health and the viscosity of the blood.
Hunter gatherer diet is the healthiest
She took the nutrients that were important to her brain and she designed a food plan to get those nutrients
Dinner plate is 3 cups of veggies…greens rich in BACK (B12 requires animal protein)vit k is important for endothelial health, need minerals for the vitamins to help.
Sulphur supports brain
Cabbage, onion and mushrooms +sulfur
Colors=flavonoids, antioxidants, retinas mitochondria and toxin removal
Wild fish= rich in omega 3 fatty acid= myelin and straight teeth
Myelin and straight teeth…grass fed meat and organ meats+ coQ10, vitamins, minerals,
2-3xper week
liver has more vit and minerals than broccoli
seaweed= iodine which helps with myelin and toxin removal and decreases cancer
food allergies are hard to diagnose.
Gluten sensitivity and brain diseases
Celiac, gluten ataxia, gluten encephalopathy, autism, ALS, seizures
Dairy free casein is a cause of sensitivity esp if you are gluten sensitive.
Mitochondria-inflammation issue
Depression, bipolar, anxiety, ocd, eating disorder, dementia, learning disability, autism, schizophrenia, hypertension, DM, arthritis,
Ann Boroch
Healing ms with nutrition and detoxification
Inflammation and infection is what causes the problems
Read Dr Cooks book on the yeast connection
She gave up gluten, alcohol and sugar.
If you don’t maintain balance the yeast comes back worse
Candida diet again and took Nystatin and removed her fillings.
17years of symptom free
what creates ms
inflammation and infection environment, GI problems, diet, infections,
Everyone with MS has candida and virus. The genes turn on because of the environment. If some of it goes to the nervous sys you have ms. If it goes to the muscles you have fibromyalgia
Candida most grossly ignored microorganism in western medicine, yeast/fungal toxins disrupt communication of the body. Antibiotics, steroids, chemo, HRT, sugar stress and alcohol
Infection…antibiotics…destroy good and bad bacteria in the GI tract…candida overgrowth…toxins from yeast and fungus weaken the immune system.
Maldigestion, malabsorption, leaky gut, compromised liver function, weakened immune system compromised BBB, autoimmune disease, Alzheimer, cancer, and other chronic progressive conditions. The endothelium gets leaky. Yeast overgrowth decreases communication in the body. Remove infection and inflammation.
Takes diligence and commitment are essential. The loss of intestinal barrier function is necessary to develop autoimmunity.
Link between candida and ms
Dr perlmutter the frequency of focal white matter lesions in pts with inflammatory bowel disease is almost as high as those in pts with ms. These findings provide convincing evidence supporting that relationship.
Environmental toxicity in our air, water, xenoestrogens (pcb, bpa, phthalates)
Vaccination, cell phone, cordless phone, tv and computers,
Noise pollution
Recommendation to neutralize environmental toxicity
Ionic foot baths, air purifier, water system or bottled water company, use speaker function when talking on cell , non toxic cleaning products.
STRESS:
Ability to handle emotional mental and physical demands of life, we all have stress , stress and fear are the number one body breakers, stress increases cortisol secreted by the adrenal glands, which inflames the body,
How to turn this around
Candia diet, detoxify and manage stress
Detoxification:
Supplements probiotics, vit c3, e c coQ10 b12, evening primorose oil,oregano oil, n- acetyl cysteine, turmeric resveratrol
Dr Chaudhary(neurologist and Ayurvedic doctor(Devin’s doctor)
Ayurvedic perspective on MS
Moving forward sometimes mean looking backward
“Science of life” ancient medical system of India, 5,000year old
objective to prolong life and promote perfect health
to completely eradicate disease and dysfunction of the body
you can reverse and irradicate disease
5 basic elements in the form of dosha
vata, pitta, kapha
MS pts are mostly vata or pitta
Everyone has these elements and are usually a combination. Many things can disturb the natural balance of the doshas, stress, unhealthy diet or routine, weather, the disturbance shows up as disease
Ayurvedic docs prescribe holistic, multi modality tx programs to bring the doshas back into balance.
A specialized ayurvedic hx and exam
Pulse diagnosis
There is a link between the GI tract and the nervous system the ayurvedic tx is 80% diet.
the underlying pattern of imbalance at the basis of current or future disease
the patients constitutional type or mind body type
vata
governs bodily functions concerned with mvmt main imbalance in MS
blood circulation, breathing, elimination, heartbeat
space and wind
pitta
governs bodily functions concerned with heat and temp control
pitta people are type A
sharp mentally have mildest form of ms if you can get under control
kapha
muscle, fat , bone, joints
multi modality therapeutic approach
diet and nutrition, herbs, meditation, breathing exercises, daily self massage with herbalized oil, yoga, seasonal purification procedures
NO MS PATIENTS HAVE NORMAL DIGESTION
Digestive tea Recipe
Boil 4-5 cups of water in the morning.
Add ½ tsp of the following seeds to the water and continue to let steep for at least 10 min with the lid on.
.whole cumin seeds
.whole coriander seeds
.whole fennel seeds
Strain out the seeds and pour the liquid into a thermos. Sip the liquid throughout the day. Start fresh with a new batch of tea each morning. If the tea is too strong or if you experience some initial discomfort, reduce the amount of the seeds to ¼ tsp for 2 weeks and then increase it back to ½ tsp
Fred Fox IRB and importance of collecting data
Discussed the FDA warning and the need for docs to get IDE to continue to study CCSVI and treat.
We had a yummy gluten free lunch and after the conference we had a gluten free reception with delicious snacks.
http://www.facebook.com/groups/130599856961335/