Cortical Lesions in Multiple Sclerosis - facebook prikbord

The conclusion to this article tells the story:

In conclusion, the two studies published in this issue of Brain add interesting new information to the enigma of cortical lesion pathogenesis in multiple sclerosis. The data support the view that meningeal inflammation plays an important role in the induction and propagation of cortical pathology in multiple sclerosis, but they also indicate that additional and, thus far, unknown mechanisms are necessary to trigger widespread demyelination and neurodegeneration in the cortex.

http://www.medscape.com/viewarticle/773247?src=nl_topic

My comment: It is not just about the immune system. It is becoming clearer and clearer that there are other processes at work. The immune system is doing what it is meant to do and that is clear up dead and dying tissue. Inflammation is never pleasant, we just have to think of what a cold feels like. The symptoms of the common cold are all due to the immune system doing its job. Inflammation in the brain is more unpleasant and leaves us with a worsening condition, but what is causing the degeneration of the myelin in the first place... that is the real question?