Magnesium Deficiency Causes Loss of Response to Intermittent Hypoxia in Paraganglion Cells http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707206/


Magnesium Deficiency Causes Loss of Response to Intermittent Hypoxia in Paraganglion Cells
www.ncbi.nlm.nih.gov
Magnesium deficiency is suggested to contribute to many age-related diseases. Hypoxia-inducible factor 1a (HIF-1a) is known to be a master regulator of hypoxic response. Here we show that hypomagnesemia suppresses reactive oxygen species (ROS)-induced HIF-1a activity in paraganglion cells of the adr…