C1-C2 X-Ray assessment of misalignment parameters in patients with Chronic Cerebra-spinal Venous Insufficiency and Multiple Sclerosis versus patients with other pathologies.

“...Conclusions
The X-Ray results illustrated above show that in patients with MS, compared to control group without neurological disease, there is a statistically significant difference about the effective anterior intrusion of C1 and C2 (p = 0.0008) and a right laterality (p = 0.0426). The presence of an endovascular hemodynamic conditions CCSVI-type 1, intrinsic to the vessel itself, suggests the treatment of these patients with an endovascular approach. This approach instead would be not recommended in patients with extrinsic compression CCSVI-type 2. This second kind of patients may take the specific physiotherapy in order to decompress the neck veins. The treatment of patients with mixed obstruction CCSVI-type 3 may be an indication to both angioplasty treatment than extra-vascular decompression.

The detection of an alteration in the alignment of the first two cervical vertebrae in patients with MS further emphasizes the role of cerebrospinal venous drainage in the pathogenesis and progression of this disease. To find these two specific radiological dislocation of the C1-C2 vertebrae allows us to hypothesize, in these subjects, a risk of presence of a CCSVI and of developing a MS.

Considering the novelty of this work and the total absence of scientific similar workable to confirm this data, it is necessary to continue these studies in order to improve the clinical management of these patients and to perform therapeutic strategies based on venous decompressive treatments both surgical that manipulatives...”

full paper: http://www.domenicoricci.it/images/lavori_scientifici/X-ray_C1-C2.pdf