New research presented by NIH shows vascular connection in MS as related to fibrinogen. In 2006, prior to proposing CCSVI, Dr. Zamboni presented a paper noting the remarkable similarity between Chronic Venous Disease (CVD), and MS, including similar lesions and iron/fibrinogen deposition.


NIH-funded researchers show possible trigger for MS nerve damage, November 27, 2012 News Release - N
www.nih.gov
High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.