Research into neurovascular diseases (like MS, Alzheimer's, Parkinsons) has viewed disease thru the narrow "neurocentric" view. But the brain is connected to the rest of the body. "In this review we summarize data that support a new paradigm of disease pathogenesis, based on endothelial dysfunction and release of pluripotent mediators with effects on inflammation, vascular activation/angiogenesis and neurotoxicity."


Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesi
www.jneuroinflammation.com
Alzheimer's disease (AD) is an age-related disorder characterized by progressive cognitive decline and dementia. Alzheimer's disease is an increasingly prevalent disease with 5.3 million people in the United States currently affected. This number is a 10 percent increase from previous estimates and ...