Muscle oxygen consumption by NIRS and mobility in multiple sclerosis patients
Anna Maria Malagoni, Michele Felisatti, [...], and Fabio Manfredini

Abstract

The study of muscle metabolism by near-infrared spectroscopy (NIRS) has been poorly implemented in multiple sclerosis (MS). Aims of the study were to compare resting muscle oxygen consumption (rmVO2) at gastrocnemius in MS patients and in age-matched healthy controls (HC) measured using NIRS, and to evaluate its possible relationship with patients’ mobility.

“...Conclusions
rmVO2 values measured by NIRS were found to be significantly higher in MS patients compared to HC, and in low versus better performing patients. Such parameter might represent a marker of peripheral adaptations occurred to sustain mobility. It might be potentially useful in a clinical setting for assessing the level of skeletal muscle metabolic impairment, and for monitoring the progression of the disease, therapeutic treatments or rehabilitative programs.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717115/#!po=3.12500


Muscle oxygen consumption by NIRS and mobility in multiple sclerosis patients
www.ncbi.nlm.nih.gov
The study of muscle metabolism by near-infrared spectroscopy (NIRS) has been poorly implemented in multiple sclerosis (MS).