Magnesium deficiency promotes a pro-atherogenic phenotype in cultured human endothelial cells via activation of NFkB
Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseVolume 1802, Issue 11 Nov. 2010

“Conclusion -- Our data indicate that low Mg promotes endothelial dysfunction by activating NFkB which, in turn, triggers a transcriptional program leading to the acquisition of a pro-inflammatory and pro-atherogenic phenotype. Based on epidemiological, cellular and molecular evidence, we propose that broadly correcting nutritional intakes of Mg might represent a simple and inexpensive solution that contributes to the prevention of atherosclerosis.”
learn more/full paper: http://www.sciencedirect.com/science/article/pii/S0925443910001262