via CCSVI in Multiple Sclerosis - MS and Endothelial Dysfunction. "In this review, we discussed in detail the concepts of structural and functional features of a healthy endothelium and endothelial dysfunction, and present the basic theory of the damage mechanism of the blood-brain barrier and the role of endothelial cells, adhesion molecules, cerebral hypoperfusion in multiple sclerosis." http://www.ncbi.nlm.nih.gov/pubmed/24416810