Breakdown of the blood brain barrier is linked to damaged pericyte cells. Protein called platelet-derived growth factor beta is shed when pericyte cells are exposed to lack of oxygen. CCSVI Alliance asks ,"Could this be from slowed cerebral perfusion - hypoxia?"

http://www.sciencenewsdigital.org/sciencenews/20150221?pg=10#pg10


Science News - February 21, 2015
www.sciencenewsdigital.org
Time can wear down the sturdiest walls, even the one that protects the brain from bad stuff in the blood. This blood-brain barrier breaks down with age, possibly playing a role in Alzheimer’s disease, a new study suggests.