Identical lesion morphology in primary progressive and relapsing-remitting MS -an ultrahigh field MRI study.

Abstract

Potential differences between primary progressive (PP) and relapsing-remitting (RR) multiple sclerosis (MS) have been controversially discussed. In this study, we compared lesion morphology and distribution in patients with PPMS and RRMS (nine in each group) using 7 T MRI. We found that gray and white matter lesions in PPMS and RRMS patients did not differ in their respective morphological characteristics (e.g. perivascular p = 0.863, hypointense rim p = 0.796, cortical lesion count p = 0.436). Although limited by a small sample size, our study results suggest that PPMS and RRMS, despite differences in disease course and clinical characteristics, exhibit identical lesion morphology under ultrahigh field MRI. http://www.ncbi.nlm.nih.gov/pubmed/?term=24781284


Identical lesion morphology in primary progressiv... [Mult Scler. 2014] - PubMed - NCBI
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