Chronische Cerebro-Spinale Veneuze Insufficiëntie

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BerichtGeplaatst: wo 01 sep 2010, 14:53 
Vergeet niet ook hier even m'n onderschrift te lezen...

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SV: de Canadese neurologen adviseren (vooralsnog) de regering grootschalig onderzoek naar CCSVI niet de subsidiëren.


http://www.healthzone.ca/health/newsfea ... -treatment

A group of leading Canadian medical experts is advising the federal government against funding clinical trials for a controversial new multiple sclerosis therapy.

The Canadian Institutes for Health Research and the MS Society of Canada held a joint meeting on research priorities for the progressive and debilitating disease last week and provided recommendations to federal Health Minister Leona Aglukkaq.

They concluded there is not enough evidence at this time to support beginning mass clinical trials for an experimental treatment – the so-called “liberation procedure” – that opens up veins transporting blood from the brain to the heart in MS patients.

“There was unanimous agreement from the scientific experts that it is premature to support pan-Canadian clinical trials on the proposed (procedure),” Alain Beaudet, president of the federal granting agency, said in a statement in advance of a news conference Tuesday. “There is an overwhelming lack of scientific evidence on the safety and efficacy of the procedure, or even that there is any link between blocked veins and MS.”

The treatment was pioneered by Italian vascular surgeon Paolo Zamboni and has been championed as a medical breakthrough by patients desperate for a way to alleviate their symptoms.

Hundreds of MS patients have been travelling around the world and paying thousands of dollars to obtain the treatment, which is not available in Canada, often against the advice of their own neurologists at home.

They have also been lobbying the MS Society of Canada and provincial and politicians to fund research into the treatment.

That is why the conclusions reached at the joint meeting are expected to be harshly criticized by patient groups.

But the experts also recommended establishing a scientific working group to monitor and analyze results from seven studies of the liberation procedure sponsored by the MS Society of Canada, which will then reach conclusions on the worthiness of the treatment.

The working group can then recommend further studies if warranted.

Saskatchewan was the first province to decide to pay for clinical trials, but Ontario has already decided against it, while leaving the door open for future possibilities.

“It is just early days yet,” Premier Dalton McGuinty told reporters in July. “It is very interesting, I think it holds some promise and our responsibility now is to work together and make sure it is something we should be supporting.”

The treatment, which is officially known as “chronic cerebrospinal venous insufficiency” (CCSVI), is based on the theory that the disease could be the result of narrowed veins in the chest and neck blocking the drainage of blood from the vein.

Inflammation and a malfunctioning immune system have traditionally been pinned as the culprits for the disease, which damages the nervous system.

The treatment method developed by Zamboni is a relatively low-risk procedure that clears blocked veins in the neck.

It has been compared to coronary angioplasty, which opens blocked arteries of heart patients.

There are about 75,000 Canadians with MS in Canada.

Source: healthzone.ca © Toronto Star 1996-2010 (31/08/10)


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