Some clarifications concerning inaccurate news spread by the media, with special reference to Dr Zivadinov’s study published in the April issue of Neurology.

Some clarifications concerning inaccurate news spread by the media, with special reference to Dr Zivadinov’s study published in the April issue of Neurology.

CCSVI is by full right to be included among the causative factors of MS since it was found in 60% of the pediatric forms of MS.

The published data - disclosed in 2010 – were already then regarded as confirming data.

The study - conducted by the researchers at the University at Buffalo on the relationship between CCSVI and MS and published in Neurology (journal of the American Academy of Neurology) on April 13, 2011 (www.neurology.org) - is causing quite a stir, but this piece of news requires some clarifications.
As a matter of fact, these studies are said to disprove the theory according to which there is a relationship between CCSVI and MS, highlighting the fact that CCSVI is not a cause but rather a consequence of MS.

Indeed, the study published in Neurology further confirms the findings of last Spring; in fact, both the study and the data it contains are the same as those disclosed in a press release in Spring 2010 and described as confirming data.

conducted by the researchers at the University at Buffalo on the relationship between CCSVI and MS and published in Neurology (journal of the American Academy of Neurology) on April 13, 2011 (www.neurology.org) - is causing quite a stir, but this piece of news requires some clarifications.
As a matter of fact, these studies are said to disprove the theory according to which there is a relationship between CCSVI and MS, highlighting the fact that CCSVI is not a cause but rather a consequence of MS.

Indeed, the study published in Neurology further confirms the findings of last Spring; in fact, both the study and the data it contains are the same as those disclosed in a press release in Spring 2010 and described as confirming data.

These findings are in line with those presented at the Live Web Forum organized by the National MS Society in Toronto on April 14, 2010, also attended by Prof Paolo Zamboni, Director of the Center for Vascular Diseases of the Ferrara University and discoverer of CSSVI, Dr Robert Zivadinov from the University at Buffalo, Dr Andrew Common, radiologist at St. Michael’s Hospital, University of Toronto, and Dr Aaron Miller, Professor of Neurology and Director of the MS Center at Mount Sinai, New York. During the Live Web Forum – followed live by physicians and patients from 5 continents - both these 4 experts and the attending scientists regarded the Buffalo study as a confirmation study. Indeed, the analysis of the data led to the conclusion that CCSVI was also a negative prognostic factor for the course of MS.

For this reason the data need to be interpreted in a different way.

Prof Zivadinov‘s findings do not prove Prof Zamboni‘s work wrong, contrary to what other sources have incorrectly reported to the media. Instead, his data strongly support the fact that – in a multifactorial perspective largely accepted by all scientists - CCSVI is by full right to be included among the causative factors of MS, since it was found in almost 60% of the pediatric forms of MS and in almost 40% of the subjects with Clinically Isolated Syndrome (Cis). Clearly, being present in most pediatric forms, it is difficult to consider CCSVI as a consequence of MS.

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