Przeglad Flebologiczny (Phlebological Review)

2011;19(1):9-14

Early results of a prospective open-label study on endovascular treatments for chronic cerebrospinal venous insufficiency in the patients with associated multiple sclerosis

T. Ludyga*, M. Kazibudzki*, P. Latacz*, M. Swierad*, J. Piegzda*, M. Hartel**, E. Kluczewska***, M. Simka*

*Euromedic Specialist Clinics

Department of Vascular & Endovascular Surgery

Studzionka, Poland

**MCD Voxel

Magnetic Resonance Unit

Zabrze, Poland

***Silesian Medical University

Department of Medical Radiology & Radiodiagnostics

Zabrze, Poland

Abstract

The aim of this paper was to document clinical improvements after endovascular treatment for chronic cerebrospinal venous insufficiency in a group of clinically defined multiple sclerosis patients. There were assessed clinical results of the treatment of 94 patients and follow-up was 6 months. We have found statistically significant improvements of clinical symptoms of multiple sclerosis measured with Multiple Sclerosis Impact Scale-29 (MSIS-29) questionnaires: in terms of total MSIS-29 scores, as well as well as of MSIS-29 physical and psychological domains. Similarly, the patients experienced an improvement of chronic fatigue syndrome measured with Fatigue Severity Scale and Epworth sleepiness questionnaires. On the contrary, no statistically significant improvement of heat intolerance occurred. Our preliminary results confirm the findings of the previous studies that have found positive effect of endovascular treatment for venous pathologies on clinical course of multiple sclerosis. These results are encouraging and warranting further studies on this topic.

http://journals.indexcopernicus.com/abstracted.php?level=5&icid=935588