This study was done in Slovakia. They had 40 MS patients and 40 healthy controls. They used ultrasound (no MR, no venography).

They found 9 healthy controls with reflux and 34 MS patients with reflux.

Conclusion: Venous reflux is significantly higher in patients with MS than in healthy controls.

They made it public here: 24. Czech and Slovak neurological conference in Hradec Kralove (Czech republic) 24.-27. Nov. 2010.

ENGLISH TRANSLATION:

Cesk Slov Neurol N 2010; 73/106 (Suppl 2)

Incidence of venous reflux in patients with multiple sclerosis - a prospective study

Nosal V1, Chicken E1, J1 Michalik, Kantorová E1, W1 Sivák, Zelen(ák K2

JLF UK and Martinská UN:

1Neurologic Clinic, 2Radiodiagnostic Clinic

Chronic cerebrospinal venous insufficiency (CCSVI) is one of the hypotheses explaining the etiopathogenesis of multiple sclerosis. Incidence of venous reflux in internal jugular vein verified by ultrasound is one of the projected markers of CCSVI. Objective of the study was to verify the incidence of venous reflux in internal jugular vein in patients with multiple sclerosis compared with healthy population. The study included 40 patients with multiple sclerosis and 40 healthy subjects, paired by sex and age. Examination was carried out by ultrasound was studied and the incidence of reflux in internal jugular vein. Results were statistically processed using McNamara's test. In the control group, 9 patients had reflux present, while in MS patients reflux was present in 34 cases, representing a statistically significant difference (p = 0.412). Finally, it can be concluded that patients with multiple sclerosis have a significantly increased incidence of venous reflux compared with the control group.

Sources:

http://www.csnn.eu/pdf/CSNN_Supple_hradec.pdf

http://www.thisisms.com/forum/chronic-cerebrospinal-venous-insufficiency-ccsvi-f40/topic7797-360.html

http://www.facebook.com/notes/alessandro-rasman/incidence-of-venous-reflux-in-patients-with-multiple-sclerosis-a-prospective-stu/299075760106898