by Chris D. Meletis, ND
We have long known that N-acetylglucosamine (NAG) is often used to support GI health. This is why it is often included in GI support products. We know that a healthy gut is the foundation for overall wellness, particularly realizing that 70 percent plus of the immune system resides in the gut. Yet, now there is another consideration. A study conducted at UC Irvine has shown some promising research that NAG may strengthen the myelin sheath around the brain and spinal cord.
The researchers report in The Journal of Biological Chemistry that they discovered that NAG inhibited the growth and function of T-cells that inappropriately direct the immune system to break down myelin tissue that surrounds and insulates nerves. The study investigators cautioned that more human studies are required to assess the full potential of the approach.
On a side note, the NAG study was funded by the National Institutes of Health and the National Multiple Sclerosis Society. Of course consulting one’s health care provider is always important when looking to potentially balance the immune system.
It should be noted that NAG is similar yet different than plain glucosamine sulfate or HCl.