The scarring is caused by degeneration of the myelin. As I mention in my book, the demyelination can be caused by chronic ischemia, edema and NPH. Mechanical stretching, such as from edema or ventriculomegaly can damage myelin as well as alter nerve conduction. Myelin is also very sensitive to decreased blood flow (ischemia).

I think many MS signs and symptoms are due to thalamic dysfunction, which can be caused by chronic ischemia, edema and NPH (ventriculomegaly). The location makes the thalamus susceptible. The pituitary is also very susceptible to similar problems and is often affected by intracranial pressure problems.

CSF production is dependant upon sound arterial circulation to the choroid plexus and salt secreting cells of the ependyma. It's also dependant upon pressure gradients. In brief all of these conditions are affected by aging and I suspect CSF active and passive CSF producion and brain bouyancy decreases with age. The dura mater of the brain also ages. The combination will most likely favor the brain sinking in the cranial vault and into the foramen magnum, which I call a pressure cone in my book.

You are right. While manipulating the TMJ or putting splints in the mouth may help some patients with MS, I don't agree with Dr. Amir's theory at all. As you said, it's backwards. Craniosacral is a good approach but not as it is currently practiced by most doctors and dentists have no background in the spine, orthopedics or neurology. UCC is much more scientific and a good approach but there is much more that can be done. The special flexion-distraction tables I have mentioned are excellent but again doctors are poorly trained and not prepared for serious neurodegenerative conditions and associated challenges such as cord tethering, cysts, syrinxes, CTE, etc.

CSF flow is just one part of the problem. It also involves arterial and venous flow, which is why I refer to the overall circulatory problems as cranial hydrodynamics. There are also problems with displacement of the brain in the vault,tethering, inflammation among other things