INTERNATIONAL ANGIOLOGY Vol. 32 - Suppl. 1 to No. 5 October 2013
XVII WORLD CONGRESS OF THE INTERNATIONAL UNION OF PHLEBOLOGY Boston, September 8-13, 2013

Venous Angioplasty in Chronic Cerebro Spinal Venous Insufficiency associated with Multiple Sclerosis: Results at 2 Years Follow Up
G. Eisele1, A. Savino2, C. Schulte3, M. Cannellotto4, D. Simonelli4
1Sociedad de Flebologia y Linfologia Bonaerense, Buenos Aires, Argentina
2Centro de Educacion Medica CEMIC, Buenos Aires, Argentina
3Instituto Argentino de Diagnostico y Tratamiento, Buenos Aires, Argentina
4Centro de Educacion Medica CEMIC, Buenos Aires, Argentina

Aim. Demonstrate feasibility, tolerance and results of venous angioplasty (VA) in patients with associated Chronic Cerebro Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS)
Methods. This case study include 19 patients with confirmed MS and CCSVI between September 2010 to January 2013 and selected for VA because a poor response and/or severe intolerance to medical therapies. 10 men and 9 women presented with Recurrence-Relapse (n=14) and Secondary Progressive (n=5) MS confirmed with Mc Donald revised criteria. CCSVI lesions consisted in brain and spine venous drainage stenosis and slow flow where the diagnosis was based on Clinic and Neurologic evaluation (CNE), cervical Color Doppler Ultrasound (CDU) and jugular (JV) and azygos (AV) veins phlebography (PH). Post VA controls between 1 and 24 months include CNE and CDU evaluation. Complications related to VA were described. Wilcoxon test was used for statistical analysis in this preliminary ongoing study.
Results. CDU depicted 15 patients with JV lesions and PH confirmed 13 stenotic JV and 8 AV patients. VA was performed in 33 JV and 8 AV. CNE tests improve soon after VA with maximum effect between 6 and 12 months. After 12 to 24 months, a tendency to decrease and then to stabilize the benefits was observed in most patients. 8 patients presented JV restenosis between 1 and 12 months without major complications. Tolerance was excellent and feasibility showed appropriate results in all patients.
Conclusions. Patients with associated CCSVI and MS can improve their clinical conditions with VA that demonstrate to be safe and with and good tolerance.

Source: http://www.minervamedica.it/it/riviste/international-angiology/fascicolo.php?cod=R34Y2013S01
— mit Shirley Renshaw und 21 weitere Personen.
Foto: INTERNATIONAL ANGIOLOGY Vol. 32 - Suppl. 1 to No. 5 October 2013 XVII WORLD CONGRESS OF THE INTERNATIONAL UNION OF PHLEBOLOGY Boston, September 8-13, 2013 Venous Angioplasty in Chronic Cerebro Spinal Venous Insufficiency associated with Multiple Sclerosis: Results at 2 Years Follow Up G. Eisele1, A. Savino2, C. Schulte3, M. Cannellotto4, D. Simonelli4 1Sociedad de Flebologia y Linfologia Bonaerense, Buenos Aires, Argentina 2Centro de Educacion Medica CEMIC, Buenos Aires, Argentina 3Instituto Argentino de Diagnostico y Tratamiento, Buenos Aires, Argentina 4Centro de Educacion Medica CEMIC, Buenos Aires, Argentina Aim. Demonstrate feasibility, tolerance and results of venous angioplasty (VA) in patients with associated Chronic Cerebro Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS) Methods. This case study include 19 patients with confirmed MS and CCSVI between September 2010 to January 2013 and selected for VA because a poor response and/or severe intolerance to medical therapies. 10 men and 9 women presented with Recurrence-Relapse (n=14) and Secondary Progressive (n=5) MS confirmed with Mc Donald revised criteria. CCSVI lesions consisted in brain and spine venous drainage stenosis and slow flow where the diagnosis was based on Clinic and Neurologic evaluation (CNE), cervical Color Doppler Ultrasound (CDU) and jugular (JV) and azygos (AV) veins phlebography (PH). Post VA controls between 1 and 24 months include CNE and CDU evaluation. Complications related to VA were described. Wilcoxon test was used for statistical analysis in this preliminary ongoing study. Results. CDU depicted 15 patients with JV lesions and PH confirmed 13 stenotic JV and 8 AV patients. VA was performed in 33 JV and 8 AV. CNE tests improve soon after VA with maximum effect between 6 and 12 months. After 12 to 24 months, a tendency to decrease and then to stabilize the benefits was observed in most patients. 8 patients presented JV restenosis between 1 and 12 months without major complications. Tolerance was excellent and feasibility showed appropriate results in all patients. Conclusions. Patients with associated CCSVI and MS can improve their clinical conditions with VA that demonstrate to be safe and with and good tolerance. Source: http://www.minervamedica.it/it/riviste/international-angiology/fascicolo.php?cod=R34Y2013S01


International Angiology 2013 Ottobre;32(5 Suppl 1) - Minerva Medica - Riviste
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