Dr. Juurlink first published on the topic of slowed blood flow in the MS brain in 1998. Here is his brand new paper on hypoperfusion (slowed blood flow) as a factor in MS lesions.
"Most of the current therapeutic approaches in treating MS are based upon the thinking that the primary disorder is in immune regulation [2]. This, however, does not take into account that the first identifiable feature of MS is a breakdown in the blood-brain barrier (BBB) and that this can also occur in the retina [3], a site that does not contain myelin. This paper reviews the evidences that suggest that hypoperfusion might be a causal factor in oligodendrocyte and myelin damage that results in a frank immune attack on these structures in individuals with specific genetic backgrounds." http://www.hindawi.com/journals/msi/2013/598093/


The Evidence for Hypoperfusion as a Factor in Multiple Sclerosis Lesion Development
www.hindawi.com
Multiple Sclerosis International is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies related to all aspects of multiple sclerosis.