Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium.
"The finding that D3 and its metabolites modulate endothelial stability may help explain the clinical correlations between low serum vitamin D levels and the many human diseases with well-described vascular dysfunction phenotypes."
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140370

Vitamin D is a known modulator of inflammation. Native dietary vitamin D 3 is thought to be bio-inactive, and beneficial vitamin D 3 effects are thought to be largely mediated by the metabolite 1,25(OH) 2 D 3 . Reduced serum levels of the most commonly measured precursor metabolite, 25(OH)D 3 , is l…