Hypoperfusion of the thalamus is associated with disability in relapsing remitting multiple sclerosis.
CONCLUSION: In relapsing remitting MS, perfusion abnormalities in thalamic regions contribute to disability. These findings suggest that functional impairments of thalami, representing a major brain hub, may disturb various cerebral functions even before structural damage.
Tweet from Dr. Paolo Zamboni: "CCSVI is associated to low brain perfusion. In turn thalamus hypoperfusion to disability in Multiple Sclerosis"
https://www.ncbi.nlm.nih.gov/pubmed/27865557

J Neuroradiol. 2016 Nov 16. pii: S0150-9861(16)30169-9. doi: 10.1016/j.neurad.2016.10.001. [Epub ahead of print]