Changes in expression profiles of internal jugular vein wall and plasma protein levels in multiple sclerosis
Conclusions
This study provides for the first time expression patterns of the IJV wall, suggesting signatures of altered vascular mRNA profiles in MS disease also independently from CCSVI. The combined transcriptome-protein analysis provides intriguing links between IJV wall transcript alteration and plasma protein expression, thus highlighting proteins of interest for MS pathophysiology.
https://molmed.biomedcentral.com/articles/10.1186/s10020-018-0043-4
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