Time to Revisit Non-Pharmacological Research Approaches to Ameliorate Multiple Sclerosis Symptoms, Bernhard HJ Juurlink

Department of Anatomy and Cell Biology, College of Medicine, University of Saskatchewan, Canada, Dec. 2015

Abstract

Background: The current pharmacotherapies longest in use to treat multiple sclerosis (MS) do not slow progression to disability. The aim of this commentary is to stimulate interest in looking at MS from a new perspective. There is an abundance of evidence that MS is not primarily an autoimmune disease but is a disease where there is first damage to the blood-brain barrier as well as the oligodendrocyte-myelin unit; this damage then elicits an immune response in a subset of people that have an immune system predisposed to a attacking myelin-associated an gens. A brief overview is given of the evidence for arterial compliance problems, intracranial compliance problems, venous return problems and hypoperfusion problems in MS.

Conclusions: A rationale is given for the conduction of clinical trials examining the ability of dietary changes, hyperbaric oxygen treatment and approaches to improve venous return as means to ameliorate MS.

Full paper: http://www.jneuro.com/neurology-neuroscience/time-to-revisit-nonpharmacological-research-approaches-to-ameliorate-multiple-sclerosis-symptoms.pdf

Dr. Bernhard Juurlink: Time to Revisit Non-Pharmacological Research Approaches to Ameliorate Multiple Sclerosis Symptoms

"There are clear scientific rationales for examining the ability of angioplasty to treated obstructed venous return to ameliorate MS. There are clear scientific rationales for examining the ability of hyperbaric oxygen treatment to ameliorate MS. And there are clear scientific rationales for examining the ability of changes in diet and other lifestyle aspects to ameliorate MS. Certainly the rationales are as valid, and even more so, as those for the currently- approved [pharmacological] treatments of MS."

Dr. Juurlink is a volunteer Board member with the Canadian Neurovascular Health Society

http://www.jneuro.com/neurology-neuroscience/time-to-revisit-nonpharmacological-research-approaches-to-ameliorate-multiple-sclerosis-symptoms.pdf