"Vascular Disease in Patients with Multiple Sclerosis: A Review", Journal of Vascular Medicine & Surgery, 2016

"...Conclusion: Recent evidence suggests that vascular components may be initiating triggers for neuronal pathology and subsequent neurological manifestations of the disease. The high degree of comorbidity between vascular disease and Multiple Sclerosis suggests that vascular pathology may be an important factor causing neuronal dysfunction or degeneration in MS"

Full paper: http://www.esciencecentral.org/journals/vascular-disease-in-patients-with-multiple-sclerosis-a-review-2329-6925-1000259.pdf