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Sunday, November 20, 2016 8:33 PM | Venöse Multiple Sklerose, CVI & SVI, CCSVI shared CCSVI in Multiple Sclerosis's photo. Volg link
Researchers ask central vein in MS consensus authors--why didn't you cite Zamboni's important research???
CCSVI in Multiple Sclerosis
Researchers ask central vein in MS consensus authors--why didn't you cite Zamboni's important research???

Re: The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative.
Bernhard HJ. Juurlink MD, Dario Alpini MD, Attilio Guazzoni MD, Laura Mendozzi MD, Raffaello Pagani MD, PierluigI Stimamiglio MD, Pietro Maria Bavera MD

We read with interest the consensus statement titled "The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative" (1).
We wonder why the authors haven't cited in the notes any paper of Dr. Paolo Zamboni from University of Ferrara, Italy.
Particulary, his oldest paper titled "The big idea: iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis" published in November 2006 (2).
In that paper he readily showed the histology of the CVS, and explicitly reported the possibility to image it by the means of MR, as well.
Regards.

Disclosures: none

References:
1) Sati, Pascal, et al. "The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative." Nature Reviews Neurology (2016).
2) Zamboni, Paolo. "The big idea: iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis." Journal of the Royal Society of Medicine 99.11 (2006): 589-593.