Role of Magnesium in Vitamin D Activation and Function, The Journal of the American Osteopathic Association, 2018

“...Conclusion
Magnesium homeostasis is maintained by the delicate interactions of the intestine, bone, and kidneys. Magnesium is an essential cofactor for vitamin D synthesis and activation and, in turn, can increase intestinal absorption of magnesium and establish a feed-forward loop to maintain its homeostasis. Dysregulation in either of these nutrients can be associated with various disorders, including skeletal deformities, cardiovascular disorders, and metabolic syndrome.91 A core principle of osteopathic medicine lies in promoting the body's innate ability to heal itself. A better understanding of how magnesium supplementation might reduce complications related to vitamin D deficiency would help improve patient care.”

Full paper: http://jaoa.org/article.aspx?articleid=2673882

Uwitonze AM, Razzaque MS. Role of Magnesium in Vitamin D Activation and Function. J Am Osteopath Assoc 2018;118(3):181–189. doi: 10.7556/jaoa.2018.037.