Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes, 2016

”Significance
These data suggest that low dose iron treatments are sufficient to modify the vascular endothelium, and induce a DNA damage response.”

Full paper: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147990

Background Spontaneous reports from patients able to report vascular sequelae in real time, and recognition that serum non transferrin bound iron may reach or exceed 10µmol/L in the blood stream after iron tablets or infusions, led us to hypothesize that conventional iron treatments may provoke acu...