- The Human Magnesome –
Just a little reminder what it means for our bodies to be low in Magnesium. It’s like trying to play beautiful sinfonie by one of mankind’s greatest composers without a conductor. IT’S NOT GOING TO WORK! No matter how hard the individual of the orchestra tries to play his part perfectly. Without a conductor, the sinfonie will end up as a BIG MESS!

The human "magnesome": detecting magnesium binding sites on human proteins., BMC Bioinformatics2012

Full paper: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-13-S14-S10
“...CONCLUSION: We describe and deliver the "human magnesome", a set of proteins of the human proteome that inherit putative binding of magnesium ions. With our BAR-hMG, 251 clusters including 1,341 magnesium binding protein structures corresponding to 387 sequences are sufficient to annotate some 13,689 residues in 3,751 human sequences as "magnesium binding". Protein structures act therefore as three-dimensional seeds for structural and functional annotation of human sequences. The data base collects specifically all the human proteins that can be annotated according to our procedure as "magnesium binding", the corresponding structures and BAR+ clusters from where they derive the annotation (http://bar.biocomp.unibo.it/mg).