Dr Frank Veith and Dr Michael Dake (Veith Symposium 2015)
comment on Dr. Paolo Zamboni's presentation at the recent Veith Symposium:

Commenting on Zamboni’s presentation, Veith called the data “quite interesting, but inconclusive.”

The theory, in principle, makes sense to Michael D. Dake, MD, of Stanford University Medical School (Stanford, CA), who also commented on the data in a telephone interview with TCTMD. “Outflow insufficiency, whether you call it CCSVI or not, creates a venous obstruction that has upstream effects on the villi that reabsorbs cerebrospinal fluid and causes it to be less effective … such that there is a backup of fluid that makes the ventricles enlarge and when they enlarge there is a corresponding potential for brain atrophy and degeneration,” he noted.

Dake, an early proponent of stenting for CCSVI, said he believes Zamboni is correct that many venous abnormalities may not be sufficiently addressed by balloon intervention alone.

“What [Zamboni] is doing is somehow surgically creating better venous drainage,” Dake said. “But honestly it is unclear from this presentation exactly how he is achieving that and so that definitely requires more explanation as to what his process is for determining which patients and which abnormalities are surgical candidates.”

(Link to full article)
http://www.tctmd.com/show.aspx?id=133231