from Dr Zamboni: "If someone would correct the flow direction in a vein, she/he'll reduce the endothelial inflammation"
http://www.sciencedirect.com/science/article/pii/S0022480416301718

Conclusions

The surgical suppression of the oscillatory component of reflux modulates the inflammatory phenotype, suggesting a pivotal role of flow among factors concurring to inflammation in CVD.

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