Conclusion: In the context of a wide scientific interest for the link between venous flow and CNS disorders, the use of this model for the simulation of specific patterns (i.e., pervious vs stenotic vessels) or venous variants provides the estimate of their impact on pressures and flow in the main intracranial vessels"
/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476203/
(Thank you Sandro for the link)

The relationship between extracranial venous system abnormalities and central nervous system disorders has been recently theorized. In this paper we delve into this hypothesis by modeling the venous drainage in brain and spinal column areas and simulating ...