Readers of this page know that Marie has discussed many times how venous stasis, or slowed cerebral drainage, could be responsible for the number of viruses (such as EBV and HHV) and bacteria (such as Cpn) that have been associated with MS-by allowing these infectious agents to pass through the blood brain barrier.  Here is the Buffalo review on this topic:

The association between EBV infection and CCSVI has not yet been explored; however, it could be hypothesized that venous stasis in the superior saggital sinus due to extracranial outflow impairment could affect the drainage of bridging veins that pass through the subarachnoid space (near the meninges and EBV-infected B-cell follicles) and contribute to EBV activation. The venous stasis hypothesis in the SSS may contribute to understanding why so many different viruses and bacteria [3,111] have been linked to increased MS susceptibility risk over the last 50 years.

The blood brain barrier is supposed to keep viruses and bacteria out of the central nervous system.  Venous stasis, or slowed bloodflow, would explain why so many infectious cells are passing into the brain and spine in MS.  It just makes sense!   More studies ahead---

Joan