Emerging Roles of Endothelial Cells in Multiple Sclerosis Pathophysiology and Therapy. Clinical Neurology, March 2017

"...the complex pathogenesis of MS can only be appreciated when and if vascular contributions are recognized as a significant part of MS etiology."

Multiple sclerosis (MS) is increasingly being viewed and studied not only as an immune-mediated demyelinating and neurodegenerative disease of the human central nervous system (CNS) but as a vascular-based form of neuroinflammation. Irrespective of the MS type (relapsing-remitting (RRMS, 85%), secon...